Elixir 10- Phytoestrogen Booster
Dr Hannah Sivak
Women who decide against hormone replacement therapy (HRT) after menopause may expect slow changes in their bodies. Many are taken by surprise by the negative changes they see in their skin and hair. What happens? Our skin has receptors for estrogen, so when the estrogen levels decrease with menopause, skin and hair age very quickly because estrogen is not there anymore to pass on messages to the skin and scalp cells.*
Skin collagen content, skin thickness, and forearm bone mineral content in postmenopausal women show similar declines of between 1-2% per year after the menopause. We can't consider these declines in connective tissue structure and function "abnormal," because all women who live to a certain age will eventually experience it. But "normal" does not mean "acceptable" now that age expectancy has increased by decades. Women have the right to be annoyed at this inconvenience that makes us age too soon while we are living full and demanding lives. What was good for the cavewoman (who was going to be eaten by a lion before 50) is not good enough for modern women. At least, not for me.
If you are not going to use HRT and you are not ready to see your skin and hair age practically overnight, there are some options. For example, you can use skin and hair products that will help with the appearance of aging of skin and hair. Soy Isoflavones and nutrients (hydrolyzed collagen, hyaluronic acid, and vitamins) can help.
Our Anti-Aging Cream contains soy isoflavones and resveratrol, but if you are a woman over 50 you may need even more help. Our Elixir 10 booster is a mix of beneficial botanical extracts that can supply your skin (and scalp) with beneficial chemicals that will bind to the estrogen receptors left vacant by menopause.
Add Elixir 10 to your ready made or base creams or our Anti-aging Cream
Phytoestrogens are plant chemicals that can interact with two of the most important receptors of steroid hormones: the sex hormone-binding globulin and the cytosolic estrogen receptor. The chemical structure of phytoestrogens differs greatly and may seem very different from estradiol, but a part of the molecule is similar enough to human estrogen to fool the receptor.
For those who think that Mother Nature made these chemicals for our benefit, think again: they are part of the defense system against fungi. Also, in the 1940s, it was noticed that pastures of red clover, a phytoestrogen-rich plant, had effects on the fecundity of grazing sheep. It is likely that these plants evolved the biochemical pathways required to make these secondary metabolites to disrupt the hormonal balance in their predators, decreasing birth rates in sheep or whatever animal was having them for breakfast.
For our Elixir 10, we are using botanical extracts standardised for chemicals with estrogenic properties. As a bonus, many of these chemicals have other beneficial properties, including antioxidant and anticancer activities, and protection from UV damage. Please note that the beneficial properties enumerated below are on top of the estrogenic properties.
Ingredients: Soybean (Glycine max) Genistein, Flax (Linum usitatissimum) Lignans, Wild Yam Diosgenin, Soybean (Glycine max) Daidzein, Liquorice (Glycyrrhiza glabra) extract, Luteolin, Resveratrol, Apigenin, Phloretin, Kudzu (Pueraria lobata) Puerarin.
Kudzu Puerarin– Pueraria is a rejuvenating folk remedy in Thailand, a tradition passed on from generation to generation. The Thai name is White Kwao Krua or Kwao Keur. Besides puerarin, the 8-C-glucoside of daidzein, kudzu contains other phytoestrogens, like miroestrol, deoxymiroestrol, daidzin, genistein, and coumestrol.
Genistein and Daidzein- Stimulate the synthesis of hyaluronic acid. Genistein induces collagenation in soft tissue wound healing and inhibits tyrosine kinase.
Flax Lignans- A class of phytoestrogens with antioxidant and cancer-preventing properties, and their skin strengthening properties will help preven scarring and stretch marks.
Daidzein- Activates all three peroxisome proliferator-activated receptors (PPAR) isoforms, a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes, cellular differentiation, development, and metabolism.
Luteolin – A flavonoid with great properties: protection against lipid peroxidation and protease activation by UV radiation, anti-age, anti-itch, anti-inflammatory. We will soon start selling this active individually.
Resveratrol (3,5,4′-trihydroxystilbene)- A polyphenolic antioxidant found in grapes and red wine, blocks UVB-mediated activation of the factor NFkappa-B, and this is the mechanism of protection against photocarcinogenesis. Plant polyphenols like resveratrol may benefit the skin with anti-inflammatory and wound healing activity through their interaction with growth factor receptors (and the cytoplasmic and nuclear pathways these receptors control) besides direct antioxidant activity.
If you have a history of hormone responsive cancer or are taking tamoxifen, please ask your doctor before using this product.